Philo Judaeus De Praemiis Et Poenis Et De Exsecrationibus 145

[145] and when the veins are all relaxed and dissolved, which state is followed by a complete prostration of the harmony and due arrangement of the limbs, which were indeed previously distressed by the violent rush of a briny and very bitter stream stealthily pervading them; which, when it was shut up in a narrow passage having no easy outlet, being then pressed close and pressing other parts, conduces to the production of bitter and almost intolerable pains, from which are engendered the diseases of gout and arthritic pains and diseases, for which no salutary remedy has ever been discovered, but which are incurable by any human means.